GOntoSim

• • In this study, we propose GOntoSim, a novel method to determine the functional similarity between genes.

  • GOntoSim quantifies the similarity between pairs of GO terms, by taking the graph structure and the information content (IC) of nodes into consideration.

  • We achieved a purity score of 0.94 in contrast to 0.48 for the state-ofthe-art measures on the enzyme dataset.

  • Click here to access the web server

  • GOntoSim can be downloaded from Github

  • Reference: Kamran, A.B., Naveed, H. GOntoSim: a semantic similarity measure based on LCA and common descendants. Sci Rep 12, 3818 (2022). https://doi.org/10.1038/s41598-022-07624-3